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Tag Archives: liver disease
How Does PSC Lead to IBD?
Many patients with primary sclerosing cholangitis (PSC) also have inflammatory bowel disease (IBD), which becomes more severe after liver transplantation, researchers report in the May issue of Clinical Gastroenterology and Hepatology. These patients might require special immunosuppressive regimens. PSC is … Continue reading
What are the Effects of Albumin in Patients With SBP?
Albumin infusion prevents renal impairment and reduces mortality among patients with spontaneous bacterial peritonitis (SBP), according to a meta-analysis published in the February issue of Clinical Gastroenterology and Hepatology. SBP is a common bacterial infection among cirrhotic patients and a … Continue reading
Posted in Practice
Tagged ascites, bacterial infection, blood volume, Cirrhosis, complication, hepatitis, immune response, Inflammation, kidney, liver disease, nephrology, therapy, treatment
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New Ways to Study HCV, Genotypes 3 and 4
Researchers can now study replication of Hepatitis C virus genotypes 3 and 4 in cultured cells, described in 2 articles in the January issue of Gastroenterology. These new tools will improve our understanding of how they cause liver disease, and … Continue reading
Posted in Basic Science, Practice
Tagged antiviral, assay, Cirrhosis, DAA, drug testing, experimental system, HCV, hepatitis C virus, in vitro, laboratory, liver disease, model, replication
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Differences in HCV Infection, and Effects of Treatment, Among Countries
Hepatitis C virus (HCV) infections have developed and spread at different rates in different countries, affecting outcomes of therapy, according to the October issue of Gastroenterology. Specific details of each population must therefore be considered in designing prevention and treatment … Continue reading
Posted in Basic Science, Practice
Tagged Cirrhosis, disease progression, Epidemiology, Europe, Fibrosis, hepatitis, Liver Cancer, liver disease, transplant, United States
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How Common is Portal Hypertension in Patients With NAFLD?
Patients with nonalcoholic fatty liver disease (NAFLD) are at risk for portal hypertension and esophageal varices, according to the September issue of Clinical Gastroenterology and Hepatology. The study also shows that factors such as advanced liver disease, type 2 diabetes, … Continue reading
Posted in Practice
Tagged Cirrhosis, disease progression, fatty liver disease, Fibrosis, Inflammation, liver disease, NAFLD, NASH, Obesity, Prevention, risk factor
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Can Circulating Membrane Vesicles Promote Portal Hypertension?
Patients with cirrhosis have a large amount of circulating membrane vesicles—breakdown products from inflammation and liver cell damage. However, these ‘microparticles’ (MPs) are not simply debris; they contribute to the systemic vasodilation and portal hypertension associated with cirrhosis, according to … Continue reading
It’s Not Easy to Diagnose Intermediate-Stage Liver Fibrosis
Biopsy has a low level of diagnostic performance for liver fibrosis stages F2 and F1. The recommendation for biopsy analysis, instead of non-invasive tests, for diagnosis of intermediate stages of fibrosis is therefore misleading, according to the June issue of … Continue reading
Posted in Practice
Tagged Cirrhosis, diagnostic, HBV, HCV, hepatitis progression, Inflammation, liver disease, pathology anlysis, prognostis, response to therapy, testing
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Is Cardiac Surgery Safe for Patients With Cirrhosis?
Patients with compensated cirrhosis who undergo cardiac surgery with cardiopulmonary bypass do not have greater post-operative mortality or morbidity than other patients who receive this surgery, according to the May issue of Clinical Gastroenterology and Hepatology. Advanced liver disease is … Continue reading
Posted in Practice
Tagged ascites, cardiac surgery, Cirrhosis, Complications, heart surgery, hepatic decompensation, liver disease, risk factors, safety, therapy, treatment
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What Factors Predict Recovery From Chronic HBV Infection?
A low and rapidly decreasing level of Hepatitis B surface antigen (HBsAg) is a good sign for patients with chronic HBV infection, according to the March issue of Clinical Gastroenterology and Hepatology. Tracking progression of chronic HBV infection can be … Continue reading
Kristine Novak, PhD, Science Editor
