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Tag Archives: treatment
Is SVR12 As Good As SVR24?
In patients with chronic Hepatitis C virus (HCV) infection, a sustained viral response to treatment regimens 12 weeks after therapy (SVR12) is a good indicator that the response will be maintained until week 24 (SVR 24), based on an analysis of … Continue reading
Posted in Practice
Tagged blood level, Clinical Trial, cure, DAA, follow-up, HCV, HCV RNA, hepatitis C virus, Peg-Ifn, respones, sustained, therapy, treatment, virus
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What are the Effects of Albumin in Patients With SBP?
Albumin infusion prevents renal impairment and reduces mortality among patients with spontaneous bacterial peritonitis (SBP), according to a meta-analysis published in the February issue of Clinical Gastroenterology and Hepatology. SBP is a common bacterial infection among cirrhotic patients and a … Continue reading
Posted in Practice
Tagged ascites, bacterial infection, blood volume, Cirrhosis, complication, hepatitis, immune response, Inflammation, kidney, liver disease, nephrology, therapy, treatment
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Does a Response to Proton Pump Inhibitor Therapy Indicate GERD?
Just because a patient’s upper gastrointestinal symptoms are alleviated by proton pump inhibitors (PPIs) doesn’t necessarily mean that they have gastroesophageal reflux disease (GERD), according to the December issue of Clinical Gastroenterology and Hepatology. The efficacy of PPI therapy often … Continue reading
How do Intestinal Stem Cells get their Wnt?
Intestinal homeostasis and stem cells are not affected when Paneth cells stop producing Wnt, but Wnt is required to maintain the stem cell niche in intestinal epithelial cultures, according to a mouse study in the December issue of Gastroenterology. These … Continue reading
Posted in Basic Science
Tagged crypt, development, growth, intestine, Lgr, maintenance, mouse model, Paneth cell, stem cell, therapy, tissue regeneration, treatment, Wnt
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Can We Prevent Portal Vein Thrombosis in Patients With Cirrhosis?
The anti-clotting agent enoxaparin prevents portal vein thrombosis (PVT) in patients with cirrhosis, according to the November issue of Gastroenterology. PVT can lead to portal hypertension and reduce the blood supply to the liver—some patients with acute or extensive PVT develop severe gastrointestinal … Continue reading
What Can We Learn from a Pig Model of FAP?
A pig model of intestinal adenoma development, described in the November issue of Gastroenterology, will improve our understanding of colorectal cancer development and could be used to evaluate new therapeutics. Familial adenomatous polyposis (FAP) is an inherited disease; patients develop … Continue reading
Posted in Basic Science
Tagged Animal Model, Colon Cancer, CRC, intestinal cancer, mechanism, mouse model, pathogenesis, preclinical, treatment, Tumor
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How Dangerous Are H pylori-Negative Idiopathic Bleeding Ulcers?
Patients with a bleeding peptic ulcer not caused by Helicobacter pylori infection or non-steroidal anti-inflammatory drugs (NSAIDs) are at considerable risk of recurrent bleeding and death. Furthermore, acid-suppressive drugs do not protect these patients, according to the October issue of … Continue reading
Can Antioxidants Reduce Pain from Chronic Pancreatitis?
A randomized, placebo-controlled trial published in the September issue of Gastroenterology found that antioxidants do not reduce pain or improve quality of life in patients with chronic pancreatitis—at least for middle-aged patients with alcohol- or smoking-related disease. Chronic pancreatitis is … Continue reading
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Tagged abdominal, acute, analgesia, anti-oxidant, chonic, pain, painkiller, pancreatitis, relief, therapy, treatment
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Kristine Novak, PhD, Science Editor
A Special Issue: the Exocrine Pancreas and its Disorders
Everything you ever wanted to know about the pancreas, its development and function, and the pathogenesis and treatment of its disorders are now covered in a special issue of Gastroenterology. Pancreatology is a rapidly developing field—recent findings from molecular and genetic … Continue reading →