Category Archives: Liver/Biliary

How Does Vitamin D Lower Cholesterol?

Researchers have identified a mechanism by which vitamin D reduces levels of cholesterol. In a mouse study published in the April issue of Gastroenterology, Edwin Chow et al. show that activation of the vitamin D receptor increases cholesterol 7α-hydroxylase (CYP7A1)—an … Continue reading

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What is the Best Way to Care for Patients with Alcoholic Hepatitis?

Although alcohol-related liver disease is the 8th most common cause of mortality in the US and the 2nd leading cause of mortality among all gastrointestinal diseases, there are few therapeutic options for patients or resources to support identification of new … Continue reading

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What are Choledochoceles?

Choledochoceles are cystic dilatations of the intraduodenal portion of the common bile duct. They are often classified as Type III biliary cysts, but have distinct demographic and anatomic features, and a lower risk of malignancy than other types of choledochal … Continue reading

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Most Popular Gastroenterology and CGH Papers from 2013

As we begin 2014, we can’t help but look back at 2013 and all the incredible discoveries that were made by gastroenterology and hepatology researchers. Based on the year’s most-downloaded original research articles from Gastroenterology and CGH, exciting things are … Continue reading

Posted in Cancer, GI Tract, Liver/Biliary, Pancreas, Technology | Tagged | 2 Comments

Mapping HCV Infection in the Liver

Using single-cell laser capture and high-resolution analysis, researchers show that hepatitis C virus (HCV) infects hepatocytes in the human liver in nonrandom clusters, whereas expression of anti-viral molecules is scattered among hepatocytes. The findings are presented in the December issue … Continue reading

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Preventing Mother-to-Child Transmission of HBV

Pregnant women with Hepatitis B virus (HBV) infection are less likely to pass the virus on to babies delivered by elective cesarean section, compared to those delivered vaginally or by urgent cesarean section, according to the October issue of Clinical … Continue reading

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A New Drug for Diabetes and Fatty Liver Disease?

Obeticholic acid (OCA)—an agonist of the farnesoid X receptor (FXR)— increases insulin sensitivity and reduces markers of liver inflammation and fibrosis in patients with type 2 diabetes mellitus and nonalcoholic fatty liver disease (NAFLD), according to a study published in … Continue reading

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