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Category Archives: Technology
Special Issue: The Gut Microbiome
Gastroenterology is proud to present a special issue devoted to ‘The Gut Microbiome in Health and Disease’. The human body contains over 10 times more microbial cells than human cells. This microbiome (the commensal, symbiotic, and pathogenic microorganisms that share … Continue reading
Posted in GI Tract, Technology
Tagged bacteria, C difficile, disease, E coli, gut, health, immune regulation, intestinal, liver, microbiome, microbiota, microorganism
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Video: Gastric to Esophageal Mucosal Transplantation
In the April issue of Gastroenterology, researchers report transplantation of mucosa from a patient’s stomach to esophagus, to prevent stricture formation after circumferential endoscopic mucosal dissection of early-stage esophageal cancer. Endoscopic submucosal resection and dissection are used to remove areas of dysplasia and … Continue reading
Posted in Cancer, GI Tract, Technology
Tagged dissection, dysplasia, EMD, EMR, esophageal cancer, esophagus, gastric mucosa, resection, stomach, stricture prevention, Surgery, transplantation
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What Patient Factors Affect Bowel Preparation for Colonoscopy?
Bowel preparation is suboptimal for about one third of adults older than 55 undergoing outpatient colonoscopy, says the March issue of Clinical Gastroenterology and Hepatology. Diabetes and low level of patient engagement in their own health care contribute to less-than-optimal … Continue reading
Posted in Cancer, Technology
Tagged bowel preparation, colon cleansing, efficacy, patient factors, safety
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Is There a Way to Prevent Pancreatitis After ERCP?
Aggressive intravenous hydration with lactated Ringer’s solution reduces the incidence of pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP), but is not associated with volume overload, according to a pilot study published in the February issue of Clinical Gastroenterology and Hepatology. Pancreatitis … Continue reading
Posted in Pancreas, Technology
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Are IBD Drugs Safe During Pregnancy?
Researchers find no evidence that inflammatory bowel disease (IBD) during pregnancy, or medical treatment for IBD during pregnancy, increases risk for congenital abnormalities in children. The findings, based on a large database analysis, are published in the January issue of Gastroenterology. … Continue reading
Posted in GI Tract, Technology
Tagged 5-ASA, AZA, birth defect, complication, Crohn's Disease, dangerous, drug, IBD, neonate, pregnancy, pregnant, risk factor, safety, steroid, therapy, treatment, Ulcerative Colitis
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Most Popular Gastroenterology and CGH Papers from 2013
As we begin 2014, we can’t help but look back at 2013 and all the incredible discoveries that were made by gastroenterology and hepatology researchers. Based on the year’s most-downloaded original research articles from Gastroenterology and CGH, exciting things are … Continue reading
Can We Treat Diarrhea by Stimulating Na+ Absorption?
Drugs designed to increase intestinal absorption of sodium might be the best approach for treatment of diarrheal diseases, according to the Advances in Translational Science article in the January issue of Clinical Gastroenterology and Hepatology. Acute diarrheal diseases are the second … Continue reading
Posted in GI Tract, Technology
Tagged absorption, acute, brush border, chlorine, crypt, developing nations, diarrhea, drug development, exchange, intestine, mortality, sodium, treatment, villus
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Putting a Cap on Acid Reflux
Researchers show that a polysaccharide ‘raft’ can float on top of acid in the stomach to block its backflow into the esophagus. It reduces reflux symptoms in patients with gastroesophageal reflux disease (GERD), according to a clinical trial the December issue … Continue reading
Posted in GI Tract, Technology
Tagged antacid, burning, esophagus, GERD, meal, medicine, post-prandial, reflux, stomach acid, therapy, treatment
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Are Mitochondria Involved in Ulcerative Colitis?
Changes in mitochondrial DNA that increase levels of ATP in the intestinal mucosa protect mice from colitis, according to the November issue of Gastroenterology. Strategies to increase mitochondrial ATP production by intestinal epithelial cells might therefore be developed to treat patients … Continue reading
Posted in GI Tract, Technology
Tagged apoptosis, ATP, energy production, IBD, Inflammation, Inflammatory Bowel Disease, intestine, mechanisms, mitochondria, pathogenesis, proliferation, UC, Ulcerative Colitis
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Kristine Novak, PhD, Science Editor
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