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Kristine Novak, PhD, Science Editor
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Category Archives: Technology
Can We Treat Diarrhea by Stimulating Na+ Absorption?
Drugs designed to increase intestinal absorption of sodium might be the best approach for treatment of diarrheal diseases, according to the Advances in Translational Science article in the January issue of Clinical Gastroenterology and Hepatology. Acute diarrheal diseases are the second … Continue reading
Posted in GI Tract, Technology
Tagged absorption, acute, brush border, chlorine, crypt, developing nations, diarrhea, drug development, exchange, intestine, mortality, sodium, treatment, villus
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Putting a Cap on Acid Reflux
Researchers show that a polysaccharide ‘raft’ can float on top of acid in the stomach to block its backflow into the esophagus. It reduces reflux symptoms in patients with gastroesophageal reflux disease (GERD), according to a clinical trial the December issue … Continue reading
Posted in GI Tract, Technology
Tagged antacid, burning, esophagus, GERD, meal, medicine, post-prandial, reflux, stomach acid, therapy, treatment
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Are Mitochondria Involved in Ulcerative Colitis?
Changes in mitochondrial DNA that increase levels of ATP in the intestinal mucosa protect mice from colitis, according to the November issue of Gastroenterology. Strategies to increase mitochondrial ATP production by intestinal epithelial cells might therefore be developed to treat patients … Continue reading
Posted in GI Tract, Technology
Tagged apoptosis, ATP, energy production, IBD, Inflammation, Inflammatory Bowel Disease, intestine, mechanisms, mitochondria, pathogenesis, proliferation, UC, Ulcerative Colitis
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What is the Best Treatment for Esophageal Adenocarcioma?
Patients with esophageal adenocarcinoma (EAC) who receive endoscopic therapy survive as long as patients treated by surgery, according to the November issue of Clinical Gastroenterology and Hepatology. Esophageal cancer is a highly fatal malignancy—approximate 19% of patients survive 5 years. … Continue reading
Posted in Cancer, GI Tract, Technology
Tagged adenocarcinoma, EAC, esophageal cancer, esophagus, morbidity, mortality, neoplasm, risk factor, Surgery, survival, therapy, treatment
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Cannabis for Crohn’s Disease?
Eight weeks of therapy with Δ9-tetrahydrocannabinol (THC)-rich cannabis reduced symptoms in patients with active Crohn’s disease, according to a controlled trial published in the October issue of Clinical Gastroenterology and Hepatology. However, these effects were only temporary. The marijuana plant … Continue reading
Posted in GI Tract, Technology
Tagged cannabis, Crohn's Disease, IBD, Inflammatory Bowel Disease, intestinal inflammation, marijuana, smoking, THC, therapy, treatment
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Can a microRNA Control Inflammation in Patients With Ulcerative Colitis?
Loss of a non-coding RNA that regulates inflammation could contribute to development of ulcerative colitis (UC) in children, according to the October issue of Gastroenterology. UC and Crohn’s disease are chronic inflammatory bowel diseases that affect adults and children. These … Continue reading
Posted in GI Tract, Technology
Tagged causes, CD, Colon, gene regulation, IBD, Inflammation, mechanisms, microRNA, miRNA, mRNA, pathogenesis, post-transcriptional modification, RNA processing, translation, treatment, UC
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