Tag Archives: Animal Model

Fishing for Genes that Cause Biliary Atresia

A study of zebrafish has helped identify a susceptibility gene for biliary atresia, as reported in the May issue of Gastroenterology. Biliary atresia is a progressive fibro-inflammatory disorder of infants that involves the extrahepatic and intrahepatic biliary tree and causes … Continue reading

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What Can We Learn from a Pig Model of FAP?

A pig model of intestinal adenoma development, described in the November issue of Gastroenterology, will improve our understanding of colorectal cancer development and could be used to evaluate new therapeutics. Familial adenomatous polyposis (FAP) is an inherited disease; patients develop … Continue reading

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IBD Guardian

Researchers have identified a molecule that protects colon cells from injury in a mouse model of inflammatory bowel disease (IBD). The study, published by Beth McConnell et al. in the February issue of Gastroenterology, reports that Klf5 controls genes that … Continue reading

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