Tag Archives: Celecoxib

How Does a High-Fat Diet Contribute to Pancreatic Cancer?

Posted on December 5, 2013 by Kristine Novak, PhD, Science Editor

A high-fat diet can promote development of pancreatic cancer, but cyclooxygenase-2 (COX2) inhibitors prevent this process, according to a mouse study published in the December issue of Gastroenterology. The mechanisms appear to involve activation of oncogenic KRAS and upregulation of … Continue reading →

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Are Patients Who Take Continuous NSAIDs Receiving Gastroprotection?

Posted on April 22, 2013 by Kristine Novak, PhD, Science Editor

Among patients who continuously take nonsteroidal anti-inflammatory drugs (NSAIDs), a third of co-prescriptions for drugs to prevent gastrointestinal (GI) damage are not renewed within the next 2 years. This discontinuation increases patients’ risk of stomach pain, inflammation, or ulcers, according … Continue reading →

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