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Tag Archives: chemotherapy
Sensitizing Colorectal Tumors to Chemotherapy
Although colorectal tumors with microsatellite instability (MSI) are usually considered to have a poor response to 5-fluorouracil–based chemotherapy, researchers have identified a subset that actually respond well to chemotherapy. These tumors express a dominant-negative form of the chaperone HSP110, according … Continue reading
Posted in Cancer, GI Tract
Tagged 5-FU, apoptosis, chemosensitization, chemotherapy, chromosome instability, Colon Cancer, genetic, MSI, pharmacogenetics, prognostic, response, survival
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Can We Increase the Sensitivity of Pancreatic Cancer Cells to Chemotherapeutics?
Researchers have identified small molecules that increase the ability of chemotherapeutic agents to kill pancreatic cancer cells and slow tumor growth in mice, according to the February issue of Gastroenterology. One way that chemotherapeutics such gemcitabine, 5-fluorouracil, and platinum-based compounds … Continue reading
Posted in Cancer, Pancreas, Technology
Tagged chemotherapy, drug, efficacy, Pancreatic cancer, response, safety, sensitivity, therapy, treatment
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Surviving Childhood Cancer Increases GI Risks
Individuals who received therapy for cancer during childhood have an increased risk of developing GI complications later in life, according to Robert Goldsby et al. in the May issue of Gastroenterology. About 80% of children who receive cancer therapy survive … Continue reading
Posted in Cancer, GI Tract
Tagged adverse event, cancer treatment, chemotherapy, Colon, intestine, pediatric, radiation, risk, side-effect, stomach, Toxicity, Tumor
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