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Tag Archives: Clinical Trial
A More Effective Treatment for Achalasia
A specialized endoscopic procedure called peroral endoscopic myotomy (POEM) is a safe and effective treatment for esophageal achalasia, according to the August issue of Gastroenterology. Achalasia is an esophageal motility disorder characterized by incomplete relaxation of the lower esophageal sphincter, … Continue reading
Posted in GI Tract, Technology
Tagged achalasia, Clinical Trial, endoscopy, esophagus, motility, muscle, non-invasvie, swallowing disorder, therapy, treatment
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Long-Term Effects of Teduglutide for Short-Bowel Syndrome
The glucagon-like peptide (GLP) teduglutide is effective for long-term treatment of patients with short-bowel syndrome intestinal failure, according to the July issue of Clinical Gastroenterology and Hepatology. Short-bowel syndrome is a relatively rare condition that results from massive small bowel … Continue reading
Posted in GI Tract, Technology
Tagged bowel, Clinical Trial, drug, fluid, GLP, glucagon, intestinal surgery, intravenous nutrients, SBS, treatment
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Is SVR12 As Good As SVR24?
In patients with chronic Hepatitis C virus (HCV) infection, a sustained viral response to treatment regimens 12 weeks after therapy (SVR12) is a good indicator that the response will be maintained until week 24 (SVR 24), based on an analysis of … Continue reading
Posted in Liver/Biliary, Technology
Tagged blood level, Clinical Trial, cure, DAA, follow-up, HCV, HCV RNA, hepatitis C virus, Peg-Ifn, respones, sustained, therapy, treatment, virus
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Can We Prevent Portal Vein Thrombosis in Patients With Cirrhosis?
The anti-clotting agent enoxaparin prevents portal vein thrombosis (PVT) in patients with cirrhosis, according to the November issue of Gastroenterology. PVT can lead to portal hypertension and reduce the blood supply to the liver—some patients with acute or extensive PVT develop severe gastrointestinal … Continue reading
Treating Rumination and Supragastric Belching
Baclofen is an effective treatment for patients with rumination or supragastric belching/aerophagia, according to the April issue of Clinical Gastroenterology and Hepatology. Rumination syndrome is characterized by the effortless, often repetitive regurgitation of recently ingested food into the mouth; it … Continue reading
Posted in GI Tract
Tagged belching, Clinical Trial, esophagus, food regurgitation, nervous system, pain, stomach, swallowing problems, therapy, treatment
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Can Patients With Crohn’s Disease Ever Stop Taking Infliximab?
Half of patients with Crohn’s disease treated with infliximab experience a relapse within the first year after they stop taking the drug, according to a study published in the January issue of Gastroenterology. Drugs such as infliximab inhibit the inflammatory … Continue reading
Can We Treat Chronic HCV Infection Without Interferon?
A potent combination of 2 drugs that directly target the hepatitis C virus (HCV) is effective in patients with chronic infection, and doesn’t require interferon therapy, according to an article in the December issue of Gastroenterology. Patients infected with HCV … Continue reading
Posted in Liver/Biliary, Technology
Tagged Cirrhosis, Clinical Trial, DAA, direct acting antiviral agent, drug development, Fibrosis, HCV, hepatitis C, liver disease, therapy
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How Does Deferasirox Reduce Liver Fibrosis?
Liver fibrosis is reduced in patients with iron overload β-thalassemia and hepatitis C given the iron chelator deferasirox, according to Yves Deugnier et al. in the October issue of Gastroenterology. The liver is the main site of iron accumulation in … Continue reading
Posted in Liver/Biliary, Technology
Tagged ALT, Cirrhosis, Clinical Trial, HCV, hepatitis, iron, Ishak stage, liver diseaes, outcome, therapy
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Kristine Novak, PhD, Science Editor
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