Tag Archives: colitis

Does Thiopurine Therapy Increase Cancer Risk?

Patients with ulcerative colitis (UC) have a 4-fold increase in risk of lymphoma during treatment with thiopurines, compared to UC patients who have not been treated with these drugs, according to a nationwide cohort study in the November issue of … Continue reading

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Does Depression Increase the Risk for Inflammatory Bowel Disease?

Depression increases the risk for Crohn’s disease in women, according to a study published in the January issue of Clinical Gastroenterology and Hepatology. Psychological factors might therefore contribute to development of this disorder. Anxiety, depression, and other psychological disorders are … Continue reading

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Causes and Treatment of Very-Early Onset IBD

Many infants with inflammatory bowel disease (IBD) have genetic defects that disrupt IL-10 signaling, according to the August issue of Gastroenterology. However, these children can be successfully treated by allogeneic hematopoietic stem cell transplantation, researchers report. IBD develops mostly in … Continue reading

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Who Will Develop Pouchitis After Ileal Pouch–Anal Anastomosis?

Serum markers can be used to identify patients with ulcerative colitis most likely to have inflammatory complications after ileal pouch–anal anastomosis (IPAA), according to the May issue of Clinical Gastroenterology and Hepatology. More than 20% of individuals with ulcerative colitis … Continue reading

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Does Vitamin D Prevent Crohn’s Disease?

Women with higher intake of vitamin D are less likely to develop Crohn’s disease or ulcerative colitis, according to a study published in the March issue of Gastroenterology. Vitamin D deficiency has been described in patients with inflammatory bowel diseases … Continue reading

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Certolizumab and Remission in Some Patients With Crohn’s Disease

The drug certolizumab pegol induces remission in patients with Crohn’s disease who have high baseline levels of inflammation, according to William Sandborn et al. in the August issue of Clinical Gastroenterology and Hepatology. Patients with moderate to severe Crohn’s disease … Continue reading

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Tracking Crohn’s Therapy

Measuring blood levels of C-reactive protein (CRP), a marker of inflammation, is a good way to monitor recovery from Crohn’s disease (CD) in patients being treated with infliximab, according to Matthias Jürgens et al. in the May issue of Clinical Gastroenterology … Continue reading

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