Tag Archives: diet

How Does a High-Fat Diet Contribute to Pancreatic Cancer?

A high-fat diet can promote development of pancreatic cancer, but cyclooxygenase-2 (COX2) inhibitors prevent this process, according to a mouse study published in the December issue of Gastroenterology. The mechanisms appear to involve activation of oncogenic KRAS and upregulation of … Continue reading

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How Might Carbonation Contribute to Obesity?

Carbonation makes drinks seem less sweet than they really are, and could increase consumption of sugar and food, neuroscientists report in the September issue of Gastroenterology. It might be therefore be best for weight-loss plans to avoid carbonated beverages. Addition … Continue reading

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Overall Diet, Rather than Specific Foods, Affect Risk for Esophageal Cancer

A Mediterranean diet and overall healthy eating, rather than a particular group of foods or nutrients, reduce the risk for esophageal cancers—particularly esophageal squamous cell carcinoma (ESCC), according to the September issue of Clinical Gastroenterology and Hepatology. Although diet has … Continue reading

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Is Gluten the Culprit in Non-Celiac Gluten Sensitivity?

Rapidly fermented poorly absorbed short-chain carbohydrates, rather than gluten or other wheat proteins, might cause gastrointestinal symptoms in people who do not have celiac disease but feel better on gluten-free diets, according to the August issue of Gastroenterology. Individuals with non-celiac … Continue reading

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Molecular Mechanisms of Roux-en-Y Gastric Bypass

Many of the beneficial effects of Roux-en-Y gastric bypass (RYGB), including improved glucose homeostasis, require the actions of melanocortin-4 receptors (MC4Rs) on autonomic neurons, according to the March issue of Gastroenterology. Fasting glycemia often improves within days of RYGB (see … Continue reading

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Does Vitamin D Prevent Crohn’s Disease?

Women with higher intake of vitamin D are less likely to develop Crohn’s disease or ulcerative colitis, according to a study published in the March issue of Gastroenterology. Vitamin D deficiency has been described in patients with inflammatory bowel diseases … Continue reading

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How Do Lipids Affect Liver Disease?

Changes in lipid intake or metabolism can affect development of liver injury and fibrosis, according to two studies in mice published in the January issue of Gastroenterology. The liver is an important site of energy production and lipid metabolism. However, accumulation of … Continue reading

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