Tag Archives: efficacy

What Patient Factors Affect Bowel Preparation for Colonoscopy?

Bowel preparation is suboptimal for about one third of adults older than 55 undergoing outpatient colonoscopy, says the March issue of Clinical Gastroenterology and Hepatology. Diabetes and low level of patient engagement in their own health care contribute to less-than-optimal … Continue reading

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Should Everybody Be Tested for Celiac Disease?

Not only does celiac disease cause abdominal pain, diarrhea, and bloating—untreated disease leads to progressive bone loss and derangements, increasing the risk for early osteoporosis and fractures of the hip and vertebrae. The June issue of Clinical Gastroenterology and Hepatology … Continue reading

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Can We Increase the Sensitivity of Pancreatic Cancer Cells to Chemotherapeutics?

Researchers have identified small molecules that increase the ability of chemotherapeutic agents to kill pancreatic cancer cells and slow tumor growth in mice, according to the February issue of Gastroenterology. One way that chemotherapeutics such gemcitabine, 5-fluorouracil, and platinum-based compounds … Continue reading

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Does Menopause Affect Outcomes from Roux-en-Y Gastric Bypass Surgery?

Estradiol increases body weight loss and satiation effects of Roux-en-Y gastric bypass (RYGB) in ovariectomized rats, according to the August issue of Gastroenterology. Approximately ~85% of bariatric surgery procedures are performed on women, but little is known about the effects … Continue reading

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Successful Surgery for Children with Chronic Pancreatitis

Total pancreatectomy, accompanied by auto-transplantation of islet cells, increases the quality of life for children with severe chronic pancreatitis, according to Melena Bellin et al. in the September issue of Clinical Gastroenterology and Hepatology. Chronic pancreatitis is rare among children, … Continue reading

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New Treatment for IBS

LX1031, a drug that inhibits serotonin production, relieves symptoms and increases stool consistency in patients with nonconstipating irritable bowel syndrome (IBS), according to a study by Philip Brown et al. in the August issue of Gastroenterology. Serotonin (also called 5-hydroxytryptamine or … Continue reading

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Certolizumab and Remission in Some Patients With Crohn’s Disease

The drug certolizumab pegol induces remission in patients with Crohn’s disease who have high baseline levels of inflammation, according to William Sandborn et al. in the August issue of Clinical Gastroenterology and Hepatology. Patients with moderate to severe Crohn’s disease … Continue reading

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