Tag Archives: HCV

Mapping HCV Infection in the Liver

Using single-cell laser capture and high-resolution analysis, researchers show that hepatitis C virus (HCV) infects hepatocytes in the human liver in nonrandom clusters, whereas expression of anti-viral molecules is scattered among hepatocytes. The findings are presented in the December issue … Continue reading

Posted in Liver/Biliary | Tagged , , , , , , , , , , , , , , | 4 Comments

Are Patients Receiving the Latest Anti-HCV Drugs?

Less than 20% of patients infected with the most common Hepatitis C virus (HCV) genotype receive the latest drugs approved by the US Food and Drug Administration (FDA), according to the August issue of Clinical Gastroenterology and Hepatology. This low … Continue reading

Posted in Liver/Biliary, Technology | Tagged , , , , , , , , , , , , | 2 Comments

Is SVR12 As Good As SVR24?

In patients with chronic Hepatitis C virus (HCV) infection, a sustained viral response to treatment regimens 12 weeks after therapy (SVR12) is a good indicator that the response will be maintained until week 24 (SVR 24), based on an analysis of … Continue reading

Posted in Liver/Biliary, Technology | Tagged , , , , , , , , , , , , , | Leave a comment

New Ways to Study HCV, Genotypes 3 and 4

Researchers can now study replication of Hepatitis C virus genotypes 3 and 4 in cultured cells, described in 2 articles in the January issue of Gastroenterology. These new tools will improve our understanding of how they cause liver disease, and … Continue reading

Posted in Liver/Biliary, Technology | Tagged , , , , , , , , , , , , | 2 Comments

It’s Not Easy to Diagnose Intermediate-Stage Liver Fibrosis

Biopsy has a low level of diagnostic performance for liver fibrosis stages F2 and F1. The recommendation for biopsy analysis, instead of non-invasive tests, for diagnosis of intermediate stages of fibrosis is therefore misleading, according to the June issue of … Continue reading

Posted in Liver/Biliary, Technology | Tagged , , , , , , , , , , | 1 Comment

A Special Issue on Viral Hepatitis

The May issue of Gastroenterology features a very special supplement—“Viral Hepatitis: A Changing Field”—comprising 17 review and commentary articles from international leaders in hepatitis treatment and research. The issue provides insight into the rapid progress made in the treatment and … Continue reading

Posted in Cancer, Liver/Biliary, Technology | Tagged , , , , , , , , , , , | 2 Comments

Can We Treat Chronic HCV Infection Without Interferon?

A potent combination of 2 drugs that directly target the hepatitis C virus (HCV) is effective in patients with chronic infection, and doesn’t require interferon therapy, according to an article in the December issue of Gastroenterology. Patients infected with HCV … Continue reading

Posted in Liver/Biliary, Technology | Tagged , , , , , , , , , | 1 Comment