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Tag Archives: IBD
In Treating Crohn’s Disease, Earlier is Better
Patients receiving medical therapies when they have more complicated stages of Crohn’s disease (CD) are more likely to require surgery, researchers report in the March issue of Clinical Gastroenterology and Hepatology. The disease is most-effectively treated by drugs at its … Continue reading
Posted in GI Tract
Tagged anti-TNF, CD, drug, early, IBD, Inflammation, Inflammatory Bowel Disease, late-stage, progression, stricture, sugery, thiopurine, TNF inhibitors, treatment
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Are IBD Drugs Safe During Pregnancy?
Researchers find no evidence that inflammatory bowel disease (IBD) during pregnancy, or medical treatment for IBD during pregnancy, increases risk for congenital abnormalities in children. The findings, based on a large database analysis, are published in the January issue of Gastroenterology. … Continue reading
Posted in GI Tract, Technology
Tagged 5-ASA, AZA, birth defect, complication, Crohn's Disease, dangerous, drug, IBD, neonate, pregnancy, pregnant, risk factor, safety, steroid, therapy, treatment, Ulcerative Colitis
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Are Mitochondria Involved in Ulcerative Colitis?
Changes in mitochondrial DNA that increase levels of ATP in the intestinal mucosa protect mice from colitis, according to the November issue of Gastroenterology. Strategies to increase mitochondrial ATP production by intestinal epithelial cells might therefore be developed to treat patients … Continue reading
Posted in GI Tract, Technology
Tagged apoptosis, ATP, energy production, IBD, Inflammation, Inflammatory Bowel Disease, intestine, mechanisms, mitochondria, pathogenesis, proliferation, UC, Ulcerative Colitis
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Does Thiopurine Therapy Increase Cancer Risk?
Patients with ulcerative colitis (UC) have a 4-fold increase in risk of lymphoma during treatment with thiopurines, compared to UC patients who have not been treated with these drugs, according to a nationwide cohort study in the November issue of … Continue reading
Posted in Cancer, GI Tract
Tagged 6-mercaptopurine, azathioprine, cancer risk, colitis, DNA, EBV, IBD, immunosuppressant, Inflammatory Bowel Disease, lymphoma, purine, thiopurine
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Cannabis for Crohn’s Disease?
Eight weeks of therapy with Δ9-tetrahydrocannabinol (THC)-rich cannabis reduced symptoms in patients with active Crohn’s disease, according to a controlled trial published in the October issue of Clinical Gastroenterology and Hepatology. However, these effects were only temporary. The marijuana plant … Continue reading
Posted in GI Tract, Technology
Tagged cannabis, Crohn's Disease, IBD, Inflammatory Bowel Disease, intestinal inflammation, marijuana, smoking, THC, therapy, treatment
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Can a microRNA Control Inflammation in Patients With Ulcerative Colitis?
Loss of a non-coding RNA that regulates inflammation could contribute to development of ulcerative colitis (UC) in children, according to the October issue of Gastroenterology. UC and Crohn’s disease are chronic inflammatory bowel diseases that affect adults and children. These … Continue reading
Posted in GI Tract, Technology
Tagged causes, CD, Colon, gene regulation, IBD, Inflammation, mechanisms, microRNA, miRNA, mRNA, pathogenesis, post-transcriptional modification, RNA processing, translation, treatment, UC
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Are All Patients With IBD at Increased Risk for Colorectal Cancer?
Although inflammatory bowel disease (IBD) increases risk for colorectal cancer (CRC), the risk is only substantial among patients with long-term, extensive colitis. Furthermore, CRC risk is reduced by thiopurine therapy, according to the July issue of Gastroenterology. Laurent Beaugerie et … Continue reading
Posted in Cancer, GI Tract
Tagged CD, Colon Cancer, Colorectal Cancer, CRC, Crohn's Disease, Epidemiology, IBD, Inflammatory Bowel Disease, risk factor, UC, Ulcerative Colitis
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How Does PSC Lead to IBD?
Many patients with primary sclerosing cholangitis (PSC) also have inflammatory bowel disease (IBD), which becomes more severe after liver transplantation, researchers report in the May issue of Clinical Gastroenterology and Hepatology. These patients might require special immunosuppressive regimens. PSC is … Continue reading
What are the Effects of IBD Therapy During Pregnancy?
In pregnant women treated for inflammatory bowel diseases (IBD), infliximab and adalimumab, but not certolizumab, cross the placenta and are detected in infants up to 6 months after birth, according to the March issue of Clinical Gastroenterology and Hepatology (CGH). However, … Continue reading
Does Depression Increase the Risk for Inflammatory Bowel Disease?
Depression increases the risk for Crohn’s disease in women, according to a study published in the January issue of Clinical Gastroenterology and Hepatology. Psychological factors might therefore contribute to development of this disorder. Anxiety, depression, and other psychological disorders are … Continue reading
Posted in GI Tract
Tagged anxiety, causes, colitis, Crohn's Disease, database, depression, Genetics, IBD, Nurses' Health Study, population study, risk factor, stress
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Kristine Novak, PhD, Science Editor
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