Author
Share this page:
Tag Archives: Inflammation
What is the Best Way to Care for Patients with Alcoholic Hepatitis?
Although alcohol-related liver disease is the 8th most common cause of mortality in the US and the 2nd leading cause of mortality among all gastrointestinal diseases, there are few therapeutic options for patients or resources to support identification of new … Continue reading
Posted in Liver/Biliary
Tagged alcohol, alcoholic, Cirrhosis, damage, drugs, ethanol, Fibrosis, hepatocyte, immune response, Inflammation, Kupfer cell, liver disease, therapy, treatment
1 Comment
In Treating Crohn’s Disease, Earlier is Better
Patients receiving medical therapies when they have more complicated stages of Crohn’s disease (CD) are more likely to require surgery, researchers report in the March issue of Clinical Gastroenterology and Hepatology. The disease is most-effectively treated by drugs at its … Continue reading
Posted in GI Tract
Tagged anti-TNF, CD, drug, early, IBD, Inflammation, Inflammatory Bowel Disease, late-stage, progression, stricture, sugery, thiopurine, TNF inhibitors, treatment
1 Comment
How Does a High-Fat Diet Contribute to Pancreatic Cancer?
A high-fat diet can promote development of pancreatic cancer, but cyclooxygenase-2 (COX2) inhibitors prevent this process, according to a mouse study published in the December issue of Gastroenterology. The mechanisms appear to involve activation of oncogenic KRAS and upregulation of … Continue reading
Posted in Cancer, Pancreas
Tagged Celecoxib, COX2 inhibitor, diet, Fibrosis, Inflammation, mouse model, Obesity, Pancreatic cancer, PanIN, Prevention, risk factor, tumor progression
1 Comment
Are Mitochondria Involved in Ulcerative Colitis?
Changes in mitochondrial DNA that increase levels of ATP in the intestinal mucosa protect mice from colitis, according to the November issue of Gastroenterology. Strategies to increase mitochondrial ATP production by intestinal epithelial cells might therefore be developed to treat patients … Continue reading
Posted in GI Tract, Technology
Tagged apoptosis, ATP, energy production, IBD, Inflammation, Inflammatory Bowel Disease, intestine, mechanisms, mitochondria, pathogenesis, proliferation, UC, Ulcerative Colitis
Leave a comment
Can a microRNA Control Inflammation in Patients With Ulcerative Colitis?
Loss of a non-coding RNA that regulates inflammation could contribute to development of ulcerative colitis (UC) in children, according to the October issue of Gastroenterology. UC and Crohn’s disease are chronic inflammatory bowel diseases that affect adults and children. These … Continue reading
Posted in GI Tract, Technology
Tagged causes, CD, Colon, gene regulation, IBD, Inflammation, mechanisms, microRNA, miRNA, mRNA, pathogenesis, post-transcriptional modification, RNA processing, translation, treatment, UC
Leave a comment
How Does PSC Lead to IBD?
Many patients with primary sclerosing cholangitis (PSC) also have inflammatory bowel disease (IBD), which becomes more severe after liver transplantation, researchers report in the May issue of Clinical Gastroenterology and Hepatology. These patients might require special immunosuppressive regimens. PSC is … Continue reading
What are the Effects of Albumin in Patients With SBP?
Albumin infusion prevents renal impairment and reduces mortality among patients with spontaneous bacterial peritonitis (SBP), according to a meta-analysis published in the February issue of Clinical Gastroenterology and Hepatology. SBP is a common bacterial infection among cirrhotic patients and a … Continue reading
Posted in Liver/Biliary
Tagged ascites, bacterial infection, blood volume, Cirrhosis, complication, hepatitis, immune response, Inflammation, kidney, liver disease, nephrology, therapy, treatment
2 Comments
Kristine Novak, PhD, Science Editor
agajournals.wordpress.com 
A Special Issue: the Exocrine Pancreas and its Disorders
Everything you ever wanted to know about the pancreas, its development and function, and the pathogenesis and treatment of its disorders are now covered in a special issue of Gastroenterology. Pancreatology is a rapidly developing field—recent findings from molecular and genetic … Continue reading →