Tag Archives: insulin resistance

A New Drug for Diabetes and Fatty Liver Disease?

Obeticholic acid (OCA)—an agonist of the farnesoid X receptor (FXR)— increases insulin sensitivity and reduces markers of liver inflammation and fibrosis in patients with type 2 diabetes mellitus and nonalcoholic fatty liver disease (NAFLD), according to a study published in … Continue reading

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Which Patients With Barrett’s Esophagus Will Develop Esophageal Cancer?

Researchers have found markers to identify patients with Barrett’s esophagus (BE) at greatest risk of developing esophageal adenocarcinoma. These are described in the August issue of Clinical Gastroenterology and Hepatology. In patients with BE, part of the normal stratified squamous … Continue reading

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Does the Western Diet Promote Endotoxemia and Inflammation?

A high-fat diet can cause endotoxemia, which promotes the systemic inflammation and metabolic disorders associated with obesity, according to a human study published in the May issue of Gastroenterology. Chronic endotoxemia (the presence of endotoxins such as lipopolysaccharide in blood) … Continue reading

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