Join 231 other subscribers
Share this page:
Tag Archives: Obesity
How Does a High-Fat Diet Contribute to Pancreatic Cancer?
A high-fat diet can promote development of pancreatic cancer, but cyclooxygenase-2 (COX2) inhibitors prevent this process, according to a mouse study published in the December issue of Gastroenterology. The mechanisms appear to involve activation of oncogenic KRAS and upregulation of … Continue reading
Posted in Cancer, Pancreas Tagged Celecoxib, COX2 inhibitor, diet, Fibrosis, Inflammation, mouse model, Obesity, Pancreatic cancer, PanIN, Prevention, risk factor, tumor progression 1 Comment
How Might Carbonation Contribute to Obesity?
Carbonation makes drinks seem less sweet than they really are, and could increase consumption of sugar and food, neuroscientists report in the September issue of Gastroenterology. It might be therefore be best for weight-loss plans to avoid carbonated beverages. Addition … Continue reading
Posted in GI Tract Tagged aspartame, brain activity, brain scan, carbonation, diet, fMRI, neuroscience, Obesity, soda, soft drink, sugar, Weight Loss 1 Comment
Molecular Mechanisms of Roux-en-Y Gastric Bypass
Many of the beneficial effects of Roux-en-Y gastric bypass (RYGB), including improved glucose homeostasis, require the actions of melanocortin-4 receptors (MC4Rs) on autonomic neurons, according to the March issue of Gastroenterology. Fasting glycemia often improves within days of RYGB (see … Continue reading
Posted in GI Tract, Technology Tagged bariatric surgery, calorie intake, diet, high-fat, MC receptor, melanocortin, mouse model, nervous system, neuron, Obesity, RYGB, stomach Leave a comment
How Common is Portal Hypertension in Patients With NAFLD?
Patients with nonalcoholic fatty liver disease (NAFLD) are at risk for portal hypertension and esophageal varices, according to the September issue of Clinical Gastroenterology and Hepatology. The study also shows that factors such as advanced liver disease, type 2 diabetes, … Continue reading
Posted in GI Tract, Liver/Biliary Tagged Cirrhosis, disease progression, fatty liver disease, Fibrosis, Inflammation, liver disease, NAFLD, NASH, Obesity, Prevention, risk factor 5 Comments
Does Menopause Affect Outcomes from Roux-en-Y Gastric Bypass Surgery?
Estradiol increases body weight loss and satiation effects of Roux-en-Y gastric bypass (RYGB) in ovariectomized rats, according to the August issue of Gastroenterology. Approximately ~85% of bariatric surgery procedures are performed on women, but little is known about the effects … Continue reading
Posted in GI Tract, Technology Tagged efficacy, GLP-1 secretion, hormone, menopause, Obesity, outcome, Roux-en-Y gastric bypass, RYGB, satiety, weight gain, weight-loss surgery 3 Comments
Does the Western Diet Promote Endotoxemia and Inflammation?
A high-fat diet can cause endotoxemia, which promotes the systemic inflammation and metabolic disorders associated with obesity, according to a human study published in the May issue of Gastroenterology. Chronic endotoxemia (the presence of endotoxins such as lipopolysaccharide in blood) … Continue reading
Posted in GI Tract Tagged adipose, calorie intake, cytokine, diabetes, gut microflora, high-fat diet, insulin resistance, intestinal inflammation, nutrition, Obesity 5 Comments
What Causes Weight Gain After Gastric Bypass?
A surgical complication, rather than eating habits, can cause patients to regain lost weight after gastric bypass surgery, reports Barham K. Abu Dayyeh et al. in the March issue of Clinical Gastroenterology and Hepatology. The authors correlated increased diameter of … Continue reading
Posted in GI Tract, Technology Tagged Obesity, PPV, ROC, Surgery, Weight Loss 172 Comments