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Tag Archives: Prevention
How Does a High-Fat Diet Contribute to Pancreatic Cancer?
A high-fat diet can promote development of pancreatic cancer, but cyclooxygenase-2 (COX2) inhibitors prevent this process, according to a mouse study published in the December issue of Gastroenterology. The mechanisms appear to involve activation of oncogenic KRAS and upregulation of … Continue reading
Posted in Cancer, Pancreas Tagged Celecoxib, COX2 inhibitor, diet, Fibrosis, Inflammation, mouse model, Obesity, Pancreatic cancer, PanIN, Prevention, risk factor, tumor progression 1 Comment
Are Patients Who Take Continuous NSAIDs Receiving Gastroprotection?
Among patients who continuously take nonsteroidal anti-inflammatory drugs (NSAIDs), a third of co-prescriptions for drugs to prevent gastrointestinal (GI) damage are not renewed within the next 2 years. This discontinuation increases patients’ risk of stomach pain, inflammation, or ulcers, according … Continue reading
What are the Risks for Relatives of Patients With Colorectal Cancer?
Close relatives of people with colorectal cancer (CRC) have a significant increase in prevalence of advanced neoplasms and should be screened for cancer, according to the March issue of Gastroenterology. Relatives of patients with CRC have been shown to be … Continue reading
Posted in Cancer, GI Tract Tagged Adenoma, cancer family, Colon Cancer, colonoscopy screening, Colorectal Cancer, CRC, familial, Genetics, inherited, polyp, Prevention, risk factor, Tumor 1 Comment
Why Does Colonoscopy Protect Against Left-Sided Cancers?
Polyps with advanced pathology are significantly smaller in the right than left colon, and are therefore more likely to be missed during colonoscopy examinations, according to the December issue of Clinical Gastroenterology and Hepatology. Mortality from colorectal cancer (CRC) is … Continue reading
How Common is Portal Hypertension in Patients With NAFLD?
Patients with nonalcoholic fatty liver disease (NAFLD) are at risk for portal hypertension and esophageal varices, according to the September issue of Clinical Gastroenterology and Hepatology. The study also shows that factors such as advanced liver disease, type 2 diabetes, … Continue reading
Posted in GI Tract, Liver/Biliary Tagged Cirrhosis, disease progression, fatty liver disease, Fibrosis, Inflammation, liver disease, NAFLD, NASH, Obesity, Prevention, risk factor 5 Comments
Why are Some Immunized Children Still At Risk for HBV Infection?
Despite immunization, children born to mothers with replicating HBV (marked by hepatitis B e antigen, or HBeAg) are still at risk for infection, according to the April issue of Gastroenterology. Mother-to-infant transmission is the major cause of hepatitis B virus … Continue reading
Posted in Liver/Biliary Tagged baby, Cirrhosis, HCC, hepatitis, mother to child transmission, mother-child, pediatric, Prevention, vaccination, vaccine Leave a comment
Anti-Inflammatory Drugs Prevent Colorectal Cancer (for Some)
Aspirin and other anti-inflammatory drugs prevent colorectal cancer (CRC) in some people but not others, according to the March issue of Gastroenterology. Andrew Chan et al. found that these drugs reduce the risk of CRC only in women with high … Continue reading
Posted in Cancer, GI Tract, Technology Tagged Chemoprevention, Colon Cancer, Inflammation, Prevention 2 Comments
In CRC Screening, Location Matters
Colonoscopy screening reduces mortality from cancers of the distal, but not proximal, colon, according to a study published in the October issue of Gastroenterology. Harminder Singh et al. studied mortality from CRC among more than 55,000 people that had received … Continue reading
Posted in Cancer, GI Tract Tagged Prevention, Rectosigmoid, Right Colon, Screening Leave a comment