Tag Archives: risk factor

Are IBD Drugs Safe During Pregnancy?

Researchers find no evidence that inflammatory bowel disease (IBD) during pregnancy, or medical treatment for IBD during pregnancy, increases risk for congenital abnormalities in children. The findings, based on a large database analysis, are published in the January issue of Gastroenterology. … Continue reading

Posted in GI Tract, Technology | Tagged , , , , , , , , , , , , , , , , | 4 Comments

Can We Increase Survival of Patients with Gastric Cancer?

Researchers have identified factors that affect life expectancy of patients with stomach cancer, reported in the December issue of Clinical Gastroenterology and Hepatology. Use of these factors to increase early detection of gastric adenocarcinoma could greatly increase survival times among … Continue reading

Posted in Cancer, GI Tract | Tagged , , , , , , , , , , , , | 1 Comment

How Does a High-Fat Diet Contribute to Pancreatic Cancer?

A high-fat diet can promote development of pancreatic cancer, but cyclooxygenase-2 (COX2) inhibitors prevent this process, according to a mouse study published in the December issue of Gastroenterology. The mechanisms appear to involve activation of oncogenic KRAS and upregulation of … Continue reading

Posted in Cancer, Pancreas | Tagged , , , , , , , , , , , | 1 Comment

What is the Best Treatment for Esophageal Adenocarcioma?

Patients with esophageal adenocarcinoma (EAC) who receive endoscopic therapy survive as long as patients treated by surgery, according to the November issue of Clinical Gastroenterology and Hepatology. Esophageal cancer is a highly fatal malignancy—approximate 19% of patients survive 5 years. … Continue reading

Posted in Cancer, GI Tract, Technology | Tagged , , , , , , , , , , , | 2 Comments

Which Patients With Barrett’s Esophagus Will Develop Esophageal Cancer?

Researchers have found markers to identify patients with Barrett’s esophagus (BE) at greatest risk of developing esophageal adenocarcinoma. These are described in the August issue of Clinical Gastroenterology and Hepatology. In patients with BE, part of the normal stratified squamous … Continue reading

Posted in Cancer, GI Tract, Technology | Tagged , , , , , , , , , , | 3 Comments

Are All Patients With IBD at Increased Risk for Colorectal Cancer?

Although inflammatory bowel disease (IBD) increases risk for colorectal cancer (CRC), the risk is only substantial among patients with long-term, extensive colitis. Furthermore, CRC risk is reduced by thiopurine therapy, according to the July issue of Gastroenterology. Laurent Beaugerie et … Continue reading

Posted in Cancer, GI Tract | Tagged , , , , , , , , , , | Leave a comment

How Can We Screen for Pancreatic Cancer and its Precursors?

Individuals with invasive pancreatic cancer or high-grade dysplasia can be identified based on a specific DNA mutation in pancreatic juice samples from the duodena, according to the June issue of Clinical Gastroenterology and Hepatology. Tests for mutant TP53 might be developed to improve the … Continue reading

Posted in Cancer, Pancreas | Tagged , , | Leave a comment