Tag Archives: tumor progression

How Does a High-Fat Diet Contribute to Pancreatic Cancer?

A high-fat diet can promote development of pancreatic cancer, but cyclooxygenase-2 (COX2) inhibitors prevent this process, according to a mouse study published in the December issue of Gastroenterology. The mechanisms appear to involve activation of oncogenic KRAS and upregulation of … Continue reading

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Could Bone Marrow Cells Contribute to Stomach Cancer?

H pylori recruit bone marrow-derived cells to the gastric mucosa that contribute to tumor development, according to the February issue of Gastroenterology. H pylori¬†infection promotes gastric carcinogenesis through many mechanisms, such as causing inflammation and producing virulence factors that alter … Continue reading

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New Cell Culture Technology for Colon Cancer and Barrett’s Esophagus

A new method for long-term culture of human primary colonic epithelium provides an important tool for studying colon stem cells, adenocarcinoma, colon cancer, and even Barrett’s esophagus, according to the November issue of Gastroenterology. Self-renewal of the small intestinal and … Continue reading

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