Tag Archives: Ulcerative Colitis

Are IBD Drugs Safe During Pregnancy?

Researchers find no evidence that inflammatory bowel disease (IBD) during pregnancy, or medical treatment for IBD during pregnancy, increases risk for congenital abnormalities in children. The findings, based on a large database analysis, are published in the January issue of Gastroenterology. … Continue reading

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Are Mitochondria Involved in Ulcerative Colitis?

Changes in mitochondrial DNA that increase levels of ATP in the intestinal mucosa protect mice from colitis, according to the November issue of Gastroenterology. Strategies to increase mitochondrial ATP production by intestinal epithelial cells might therefore be developed to treat patients … Continue reading

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Are All Patients With IBD at Increased Risk for Colorectal Cancer?

Although inflammatory bowel disease (IBD) increases risk for colorectal cancer (CRC), the risk is only substantial among patients with long-term, extensive colitis. Furthermore, CRC risk is reduced by thiopurine therapy, according to the July issue of Gastroenterology. Laurent Beaugerie et … Continue reading

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How Does PSC Lead to IBD?

Many patients with primary sclerosing cholangitis (PSC) also have inflammatory bowel disease (IBD), which becomes more severe after liver transplantation, researchers report in the May issue of Clinical Gastroenterology and Hepatology. These patients might require special immunosuppressive regimens. PSC is … Continue reading

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What are the Effects of IBD Therapy During Pregnancy?

In pregnant women treated for inflammatory bowel diseases (IBD),  infliximab and adalimumab, but not certolizumab, cross the placenta and are detected in infants up to 6 months after birth, according to the March issue of Clinical Gastroenterology and Hepatology (CGH). However, … Continue reading

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Abdominal CT Radiation Risk

Patients with inflammatory bowel disease (IBD) and other gastrointestinal disorders can be exposed to high levels of radiation—mostly from abdominal computed tomography (CT) scans—reports the March issue of Clinical Gastroenterology and Hepatology. Access to high-quality facilities and technologic advances have … Continue reading

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An Immune Culprit in IBD?

Patients with Crohn’s disease or ulcerative colitis have reduced levels of an important regulator of the immune response—the receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF)—according to a study by Jonathan Goldstein et al. in the July issue of Gastroenterology. The inflammatory … Continue reading

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