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Tag Archives: therapy
How Often Do Medications Cause Liver Injury?
Drug-induced liver injury (DILI) could be more common than previously believed, according to a population-based study published in the June issue of Gastroenterology. Amoxicillin-clavulanate seems to be the most common cause, and azathioprine appears to be the most hepatotoxic. Many … Continue reading
Posted in Liver/Biliary, Technology
Tagged DILI, drugs, hepatotoxicity, Iceland, liver damage, medicine, population, prescription, side-effect, therapy, toxic
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What are the Effects of Albumin in Patients With SBP?
Albumin infusion prevents renal impairment and reduces mortality among patients with spontaneous bacterial peritonitis (SBP), according to a meta-analysis published in the February issue of Clinical Gastroenterology and Hepatology. SBP is a common bacterial infection among cirrhotic patients and a … Continue reading
Posted in Liver/Biliary
Tagged ascites, bacterial infection, blood volume, Cirrhosis, complication, hepatitis, immune response, Inflammation, kidney, liver disease, nephrology, therapy, treatment
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Can We Increase the Sensitivity of Pancreatic Cancer Cells to Chemotherapeutics?
Researchers have identified small molecules that increase the ability of chemotherapeutic agents to kill pancreatic cancer cells and slow tumor growth in mice, according to the February issue of Gastroenterology. One way that chemotherapeutics such gemcitabine, 5-fluorouracil, and platinum-based compounds … Continue reading
Posted in Cancer, Pancreas, Technology
Tagged chemotherapy, drug, efficacy, Pancreatic cancer, response, safety, sensitivity, therapy, treatment
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Does a Response to Proton Pump Inhibitor Therapy Indicate GERD?
Just because a patient’s upper gastrointestinal symptoms are alleviated by proton pump inhibitors (PPIs) doesn’t necessarily mean that they have gastroesophageal reflux disease (GERD), according to the December issue of Clinical Gastroenterology and Hepatology. The efficacy of PPI therapy often … Continue reading
Posted in GI Tract, Technology
Tagged acid, Diagnosis, drug, endoscopy, esophagus, GERD, how to identify, reflux, stomach, test, therapy, treatment
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How do Intestinal Stem Cells get their Wnt?
Intestinal homeostasis and stem cells are not affected when Paneth cells stop producing Wnt, but Wnt is required to maintain the stem cell niche in intestinal epithelial cultures, according to a mouse study in the December issue of Gastroenterology. These … Continue reading
Posted in Cancer, GI Tract, Technology
Tagged crypt, development, growth, intestine, Lgr, maintenance, mouse model, Paneth cell, stem cell, therapy, tissue regeneration, treatment, Wnt
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How Dangerous Are H pylori-Negative Idiopathic Bleeding Ulcers?
Patients with a bleeding peptic ulcer not caused by Helicobacter pylori infection or non-steroidal anti-inflammatory drugs (NSAIDs) are at considerable risk of recurrent bleeding and death. Furthermore, acid-suppressive drugs do not protect these patients, according to the October issue of … Continue reading
Can Antioxidants Reduce Pain from Chronic Pancreatitis?
A randomized, placebo-controlled trial published in the September issue of Gastroenterology found that antioxidants do not reduce pain or improve quality of life in patients with chronic pancreatitis—at least for middle-aged patients with alcohol- or smoking-related disease. Chronic pancreatitis is … Continue reading
Posted in Pancreas, Technology
Tagged abdominal, acute, analgesia, anti-oxidant, chonic, pain, painkiller, pancreatitis, relief, therapy, treatment
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What Happens After Patients are Diagnosed With Celiac Disease?
Most patients with celiac disease are not adequately followed, according to the August issue of Clinical Gastroenterology and Hepatology (CGH). Improving follow-up strategies for patients with celiac disease could improve their outcomes. Adherence to a gluten-free diet is the only … Continue reading
Kristine Novak, PhD, Science Editor
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